Biofuels: enzyme prices and productivity

Biofuels: enzyme prices and productivity

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Description: Paper is all aobut BIOFUELS ENZYME PRICES AND PRODUCTIVITY, OUR COMMITMENT TO THE ETHANOL INDUSTRY BEGINS WITH OUR GLOBAL EFFORTS AND FOCUS, The production of ethanol can come from many sources and technologies, Our enzyme solutions have evolved to meet the changing needs of the industry, OUR LATEST ENZYME EVOLUTION HAS RESULTED IN COMMERCIALLY VIABLE CELLULOSIC ETHANOL ENZYMES, WE HAVE PARTNERS THROUGHOUT THE WORLD, The efforts of many are advancing the industry.

 
Author: CYNTHIA BRYANT (Fellow) | Visits: 3272 | Page Views: 3993
Domain:  Green Tech Category: Biomass Subcategory: Biofuels 
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Short URL: http://energy.wesrch.com/pdfTR10VJY9UFKEO

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Contents:
BIOFUELS

ENZYME PRICES AND PRODUCTIVITY
CYNTHIA BRYANT GLOBAL BUSINESS DEVELOPMENT MANAGER -BIOMASS The Third Berkeley Conference On The Bioeconomy Berkeley, June 25, 2010

NOVOZYMES IN BRIEF
GLOBAL PRESENCE � Global leader in Industrial Enzymes & Microorganisms � More than 700 products used in 130 countries within >30 different industries � 5,200 employees worldwide R&D � Market leader in all main industries � 47% global market share within industrial enzymes � ~14% of sales invested in R&D 6,000 � >6,000 patents in place PERFORMANCE � 2009 global sales USD 1.6B (FY 2009) 1 6B � Operating profit margin 20% (FY2009) � ROIC 20.3% (FY2009)

2009 Novozymes sales by industry
5% 3% 8% 21% 32%

31%

Detergent Food Microorganisms

Technical Feed Biopharmaceuticals

2009 market share of enzymes (industrial use)

26% 47% 6% 21%

Novozymes

Danisco

DSM

Other
2

OUR COMMITMENT TO THE ETHANOL INDUSTRY BEGINS WITH OUR GLOBAL EFFORTS AND FOCUS
� Leading provider of enzymes for ethanol in all regions where we operate � Broad insight into cellulosic ethanol � we are working on many feedstocks and technologies � U Unprecedented effort with more than 150 people dedicated to d t d ff t ith th l d di t d t Novozymes' cellulosic ethanol work � Global R&D focus on cellulosic ethanol

Novozymes' research, development and production locations

RETHINKING
FUEL
� The world is projected to increase energy use by 55% from 2005 to 2030 � Transport is the second largest energy user and the largest oil user � By 2050 there will be an estimated 2 3 billion additional 2.3 cars worldwide � 1.9 billion of these in developing countries � Improved mileage and alternative vehicles will limit but not eliminate the need for liquid transportation fuels

4

The production of ethanol can come from many sources and technologies
Raw material Production process End product

Biomass

Collection
Other crops

Cooking

Enzymes
Residues Lignin; Energy, biochemical

Residues DDGS; Feed

Raw starch hydrolysis

Fermentable sug gar

Milling

Cooking

Enzymes

Milling
Classical corn

Enzymes

Ethanol

Residues DDGS; Feed

Milling
Sugar cane

Cooking Cooking

Enzymes

Residues R id DDGS; Feed

Extraction
Residues Bagasse; Energy
5

*In the US Department of Energy Biomass-model the lignin residue is burned to power the production plant

US fuel ethanol production has been growing for two decades...
12000 10000 8000
M MGY

6000 4000 2000 0

Source: Renewable Fuels Association

...and as a part of that growth, the evolution and growth of our enzyme solutions has progressed
Past
Wild-type enzymes Best suited for wetmill processes Basic liquefaction and starch conversion Suboptimal performance for drymill production

Present
Improved genetic diversity di it High-throughput screening Protein engineering for intelligent enzyme design

Future
IMPR ROVED EFF FICIENCY AND NEW PROCESSE A P ES
7

Advanced performance f Ethanol process breakthroughs Remaining starch will be converted to ethanol Beyond Fermentation
Creation of value-added co-products Reduced energy usage Reduced water usage

Alternative substrates other t a co than corn
NOVOZYMES BIOINNOVATION

Our enzyme solutions have evolved to meet the changing needs of the industry h h d f h d

Higher performance

Stronger concentrates

New concepts

Just as starch based ethanol went through a steep g growth p period, we expect the same for cellulosic , p ethanol
30000 25000 20000 SEAIA

MGY

15000 10000 5000 0

CWE LA China Chi NA

2 2010

2 2011

2 2012

2 2013

2 2014

2 2015

2 2016

2 2017

2 2018

2 2019

2 2020

2 2021

Source: Public plant listings, government policies

2 2022

THERE IS LARGE POTENTIAL FOR MANY CELLULOSIC ETHANOL FEEDSTOCK ALTERNATIVES AND TECHNOLOGIES
Adjusted feedstock potential Estimate Production in million gallons per year (MGY) based on adjusted feedstock
Corn Stover Corn Stover Corn Cobs Corn Cobs Wheat Straw Wheat Straw Sugarcane Bagasse Sugarcane Bagasse Wood Wood

India India

China China

Brazil Brazil

EU EU

US US 0 0 50 5.000 100 150 200 10.000 15.000 250 20.000
MMT/year

300 350 400 450 25.000 30.000 35.000

500 40.000

MGY

Assumed 77% process conversion efficiency on all substrates utilizing C5 and C6 sugars Source cob:stover ratio used: 19.5: http://www.ars.usda.gov/research/publications/publications.htm?SEQ_NO_115=235194

OUR LATEST ENZYME EVOLUTION HAS RESULTED IN COMMERCIALLY VIABLE CELLULOSIC ETHANOL ENZYMES

The first commercially viable enzyme for cellulosic ethanol
11

An expanded R&D approach is providing Novozymes with broader insight
Highly interrelated technology and process choices Novozymes leverages advanced R&D tools and enzyme application know-how

Pre-treatment
� Open fiber � Increase water access � Enzyme accessibility � Minimize sugar loss Minimize sugar loss � Minimize inhibitors formed � Catalyst/auto hydrolysis � Temp/time/ technology

Hydrolysis
� Degrade polymers � Substrate viscosity/energy � Avoid effect of Avoid effect of Inhibitors � Solid load � Liquid displacement � Find superior enzymes/novel cocktails � Temperature/pH/fed batch y gy � Understand synergy effects

Fermentation
� Avoid effect of inhibitors � Avoid infection � Conversion of sugars Conversion of sugars � C5 fermenting organism � Handling of residual fibers � Yeast dosage/ cost

Applied discovery Reduce process costs via holistic innovation

13

13/07/2010

NOVOZYMES PRESENTATION

Novozymes Novozymes' Cellic� product family is enabling commercial viability
Enzyme costs are becoming a smaller and smaller percentage of the total process costs Production costs are coming in line with corn based ethanol costs

WE HAVE PARTNERS THROUGHOUT THE WORLD...

Inbicon Lignol Greenfield Poet Fiberight ICM PRAJ M&G p COFCO & Sinopec

CTC

...WHO ARE CONTINUING TO MAKE WHO ADVANCEMENTS IN BIOFUELS
14

PROCESS INTEGRATION & OPTIMZATION PARTNER: GREENFIELD ETHANOL
Reduction in Enzyme Cost
100% 90% 80% Relative Enzyme Cost 70% 60% 50% 40% 30% 20% 10% 0%

Novozymes Cellic� CTec2 � 20x reduction in enzyme cost in three years � Validated in 5-T hydrolysis reactor � Two 50% reduction step changes from enzyme improvement f � 3 years with repeatable results at multiple scales

GreenField Ethanol � Largest fuel ethanol producer in Canada � R&D facility in Chatham, Ontario � 1 ton/day pilot plant yp p � Focus on corn cob and screening other feedstocks

2007 Initial Level

2008 Process Improvement

2009 CTec

2010 CTec2

15

MOVING TO HIGHER TOTAL SOLIDS PARTNER: LIGNOL
About Lignol: � Integrated pilot plant � Upstream extraction of lignin and fl d hemicellulose yields pretreated cellulose enriched biomass solids (~90%+) � S Separation of biomass components fb into clean streams provides value-added products
100 95
Gluca an-to-Glucose Con nversion (%)

Cellic CTec Cellic CTec2

90 85 80 75 70 65 60 55 50 Enzyme Dose 1 12% Total Solids Enzyme Dose 1

� 20% reduction in enzyme costs in less than 4 months � L Lower capital costs are reachable it l t h bl with increased performance at higher total solids � Higher conversion yields due to the ability abilit to con e t recalcitrant convert ecalcit ant cellulose

Enzyme Dose 2

16% Total Solids

16

The efforts of many are advancing the industry
Roadmap for cellulosic ethanol deployment

Phase 1 2000-2009
Lab-to-pilot Lab to pilot scale
�Significant reduction in enzyme cost and overall ethanol production cost �Pilot plants running using various feedstocks �Demonstration-scale plants being built

Phase 2 2010-2011
DemonstrationDemonstration scale
�Enzyme for commercial -scale production launched and first processes ready for up-scaling �Demonstration-scale plants operating �Commercial-scale plants being built

Phase 3 2012CommercialC i l scale
�First commercial-scale p plants to commence �Large-scale demand for cellulosic bioethanol in the US and elsewhere

The US forecast has over 250 MGY of cellulosic ethanol capacity online by 2013
120 100 80 60 40 20 0

Forecasted Cellulosic Ethanol Capacity (MGY)

100.00

25.00 3.90 7.00 0.14 0.19 1.50 0.25 5.00 0.02

35.00 35 00 20.00 2.20 15.00

25.00 1.50

18.00

15.00

DuPont/Danisco

DuPont/Danisco

R RSE Pulp & Che emical, LLC

2010

2011

2012

2013

Most of the 2010 projects appear to be on track to be operational in this year We expect others to be announced as companies finalize business cases and secure financing for pilot and demo scale facilities in the next 1-2 years
18

DuPont/Danisco

Citr rosuco

bengoa Ab

Co oskata

POET

Myriant/U of FL U

els C2 Biofue LLC

Range Fuels e

Zea aChem

Bluefire Ethanol E

Fiberig LLC ght

West Bi iofuels

Ver renium

Iogen

ICM

THE BENEFITS OF ETHANOL LEAD

TO A PROMISING FUTURE
Biofuels provide economic, energy and environmental gy benefits �and government support is critical Enzymes are a tool for commercialization and for further f h process efficiencies ff Together with our partners, we are continuing to improve biofuel production

19

Read more about how we are developing technology together with our partners at www.bioenergy.novozymes.com bi

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